Personal Information

Dr. Pankaj Gupta

Assistant Professor (DST Inspire)
Department of Chemistry

Ph. D. – Indian Institute of Technology Roorkee; Post-doc. – (University of Cincinnati, USA); (Chalmers University of Technology, Sweden)

pankaj.gupta@curaj.ac.in

Electroanalytical Chemistry,

Bioelectrochemistry,

Organic Electrochemistry

Electrochemical biosensors

Nanomaterials

Energy

Wearable sensors

Biofuel cells

Current position: Assistant Professor (DST Inspire Faculty) at Department of Chemistry, Central University of Rajasthan.

Acadmic Background and Experience:

Postdoctoral Research Fellow (2021-'23) at  Chemistry and Biochemistry, Department of Chemistry and Chemical Engineering, Chalmers University of Technology, Sweden

Project: Development and fabrication of nanotip electrochemical biosensors aimed for single cells detection of neurochemical release at secretory cells.

Mentor: Prof. Ann-Sofie Cans

Postdoctoral Research Fellow (2018-'21) at Department of Chemistry, University of Cincinnati, USA

Project: Carbon nanotube fiber based microchip sensors for heavy metals and biomolecules

Mentor: Prof. Noe T. Alvarez

Assistant Manager (2017-'18) at R&D - Global Innovation Network (GIN), Siegwerk India Pvt. Ltd., Bhiwadi, Rajasthan, India (German MNC)

PhD (2017):  Department of Chemistry, Indian Institute of Technology Roorkee, Uttarakhand, India

Thesis work "Nanocomposite based sensors for voltammetric detection of biomolecules and drugs"

Supervisor - Prof. Rajendra Nath Goyal

M.Sc.(2011): Malaviya National Institute of Technology Jaipur, India 

B.Sc. (2009): University of Rajasthan, Jaipur

1. Electrochemical sensor for detection of heavy metals in drinking water: We aim to develop an electrochemical sensor to detect toxic metals such as Pb, Cu, Fe, As, Cd, and Hg (commonly found in India's water) in drinking water without adding any supporting electrolyte or reagent. Our goal is to quantify trace levels of multiple heavy metal ions simultaneously and ensure the sensor operates autonomously. The sensor can be used for onsite applications and can be fitted into the service pipeline of drinking water systems for regular monitoring of heavy metals.

Publications: 10.1016/j.aca.2021.338353, 10.1039/D2AN00724J, 10.1002/elan.202000040

2. Electrochemical and biosensors for detection of biomolecules in biofluids:  Real-time sensing presents an intriguing and cost-effective way to monitor the well-being of the human body, which would be very useful for early-stage medical diagnosis and healthcare. We work on the development of macro-, micro-, and nano-electrochemical and biosensor devices for the sensitive and selective determination of drugs (including those banned by the World Anti-Doping Agency; WADA), hormones, neurotransmitters, and DNA & RNA damage biomarkers present in biofluids such as serum, urine, saliva, and sweat. This project also involves the development of point-of-care diagnostic systems using ultrasensitive lab-on-a-chip devices, where all three electrodes are based on carbon nanotubes or printed carbon nanomaterials, and integrated with a small portable potentiostat for analyte quantification.

Publications: 10.1016/j.snb.2021.130688, 10.1021/acs.analchem.1c00360, 10.1021/acs.analchem.0c01363

3. Electrochemistry at the interface of nanomaterials: The goal of this research is to understand the fundamental electron transfer kinetics at the micro/nano interface where electrochemical reaction processes take place. Scanning electrochemical cell microscopy (SECCM) is a potential technique to reveal major new perspectives on the intrinsic electrochemical activity of nanomaterials. Scanning electrochemical techniques will be used to directly probe individual entities and in biomedical research.

Publication: 10.1021/acsaem.9b01723

4. Monitoring Quantal Fluctuations of Neurotransmitters in healthy and diseased brain: In this project, the main goal is to develop novel, cutting-edge analytical tools that provide sufficient speed and sensitivity, and are small enough to be placed directly at synapses and inside the cytoplasm of neurons. The aim is to explore the nature of quantized neurotransmitters at the synapse and to address how quantal neurotransmitter transmission relates to synaptic plasticity, learning, and memory. Additionally, the project will investigate how plaque formation in Alzheimer’s disease may affect quantal neurotransmitter transmission at presynaptic terminals.

Publication: 10.1021/jacs.4c08450 , 10.1007/978-1-0716-3742-5_5

S. No. Authors Title of Article Journal/Conference Details Journal/Conference Publication Year
1 Yuanmo Wang, Ajay Pradhan, Pankaj Gupta, Jörg Hanrieder, Henrik Zetterberg, Ann-Sofie Cans Analyzing Fusion Pore Dynamics and Counting the Number of Acetylcholine Molecules Released by Exocytosis Journal of the American Chemical Society, 146, 38, (2024), 25902-25906, 10.1021/jacs.4c08450 Journal 2024
2 Connor E Rahm, Pankaj Gupta, Vandna K. Gupta, Artur Huseinov, Ben Griesmer, and Noe T. Alvarez Impact of physical and chemical parameters on square wave anodic stripping voltammetry for trace Pb2+ detection in water RSC Analyst, 147, (2022), 3542-3557, DOI: 10.1039/D2AN00724J Journal 2022
3 Pankaj Gupta, Vandna K. Gupta, Artur Huseinov, Connor E. Rahm, Kiera Gazica, Noe T. Alvarez Highly sensitive non-enzymatic glucose sensor based on carbon nanotube microelectrode set Sensors and Actuators B, Elsevier, 348 (2021), 130688, DOI: 10.1016/j.snb.2021.130688 Journal 2021
4 Pankaj Gupta, Connor E Rahm, Benjamin Griesmer and Noe T. Alvarez Carbon Nanotube Microelectrode Set: Detection of Biomolecules to Heavy Metals Analytical Chemistry, ACS, 93, 20, (2021), 7439-7448, DOI: 10.1021/acs.analchem.1c00360. Journal 2021
5 Pankaj Gupta, Connor E Rahm, Dehua Jiang, Vandna K. Gupta, William R. Heineman, Gusphyl Justin and Noe T. Alvarez Parts per trillion detection of heavy metals in as-is tap water using carbon nanotube microelectrodes Analytica Chimica Acta, Elsevier, 1155, (2021) 338353, 1-11, DOI: 10.1016/j.aca.2021.338353 Journal 2021
6 Pankaj Gupta, Kyrus Tsai, Chethani K. Ruhunage, Vandna K. Gupta, Connor E Rahm, Dehua Jiang and Noe T. Alvarez True Picomolar Neurotransmitter Sensor Based on Open-Ended Carbon Nanotubes Analytical Chemistry, ACS, 92, 12, (2020), 8536-8545, DOI: 10.1021/acs.analchem.0c01363 Journal 2020
7 Connor E Rahm, Fernando Torres-Canas, Pankaj Gupta, Philippe Poulin, Noe Alvarez Inkjet Printed Multi‐Walled Carbon Nanotube Sensor for the Detection of Lead in Drinking Water Electroanalysis, Wiley, 32, 7, (2020), 1533-1545, DOI: 10.1002/elan.202000040 Journal 2020
8 Pankaj Gupta, Robert A. Lazenby, Connor E. Rahm, William R. Heineman, Elke Buschbeck, Ryan J. White, and Noe T. Alvarez Electrochemistry of Controlled Diameter Carbon Nanotube Fibers at the Cross Section and Sidewall ACS Applied energy material, ACS, 2, 12, (2019), 8757−8766, DOI: 10.1021/acsaem.9b01723 Journal 2019
  1.  Yuanmo Wang, Ajay Pradhan, Pankaj Gupta, Jörg Hanrieder, Henrik Zetterberg, Ann-Sofie Cans, “Analyzing Fusion Pore Dynamics and Counting the Number of Acetylcholine Molecules Released by Exocytosis”, Journal of the American Chemical Society, 146, 38, (2024), 25902-25906, 10.1021/jacs.4c08450.
  2.  Sunita Bishnoi, Ashutosh Sharma, Rahul Singhal, Pankaj Gupta, Rajendra N. Goyal, “Electrochemical sensing of chlorpyrifos, a carcinogen responsible for breast cancer, in milk and plasma of lactating mothers”, Electroanalysis, 34, (2022), DOI: 10.1002/elan.202200238.
  3.  Connor E Rahm, Pankaj Gupta, Vandna K. Gupta, Artur Huseinov, Ben Griesmer, and Noe T. Alvarez, “Impact of physical and chemical parameters on square wave anodic stripping voltammetry for trace Pb2+ detection in water”, RSC Analyst, 147, (2022), 3542-3557, DOI: 10.1039/D2AN00724J.
  4.  Pankaj Gupta, Vandna K. Gupta, Artur Huseinov, Connor E. Rahm, Kiera Gazica, Noe T. Alvarez, “Highly sensitive non-enzymatic glucose sensor based on carbon nanotube microelectrode set”, Sensors and Actuators B, Elsevier, 348 (2021), 130688, DOI: 10.1016/j.snb.2021.130688.
  5.  Pankaj Gupta, Connor E Rahm, Benjamin Griesmer and Noe T. Alvarez, “Carbon Nanotube Microelectrode Set: Detection of Biomolecules to Heavy Metals”, Analytical Chemistry, ACS, 93, 20, (2021), 7439-7448, DOI: 10.1021/acs.analchem.1c00360.
  6.  Pankaj Gupta, Connor E Rahm, Dehua Jiang, Vandna K. Gupta, William R. Heineman, Gusphyl Justin and Noe T. Alvarez, “Parts per trillion detection of heavy metals in as-is tap water using carbon nanotube microelectrodes”, Analytica Chimica Acta, Elsevier, 1155, (2021) 338353, 1-11, DOI: 10.1016/j.aca.2021.338353
  7.  Pankaj Gupta, Kyrus Tsai, Chethani K. Ruhunage, Vandna K. Gupta, Connor E Rahm, Dehua Jiang and Noe T. Alvarez “True Picomolar Neurotransmitter Sensor Based on Open-Ended Carbon Nanotubes”, Analytical Chemistry, ACS, 92, 12, (2020), 8536-8545, DOI: 10.1021/acs.analchem.0c01363.
  8.  Connor E Rahm, Fernando Torres-Canas, Pankaj Gupta, Philippe Poulin, Noe Alvarez, “Inkjet Printed Multi‐Walled Carbon Nanotube Sensor for the Detection of Lead in Drinking Water” Electroanalysis, Wiley, 32, 7, (2020), 1533-1545, DOI: 10.1002/elan.202000040. 
  9.  Pankaj Gupta, Robert A. Lazenby, Connor E. Rahm, William R. Heineman, Elke Buschbeck, Ryan J. White, and Noe T. Alvarez, “Electrochemistry of Controlled Diameter Carbon Nanotube Fibers at the Cross Section and Sidewall”, ACS Applied energy material, ACS, 2, 12, (2019), 8757−8766, DOI: 10.1021/acsaem.9b01723.
  10.  Mamta Raj, Pankaj Gupta, Rajendra N. Goyal, “Graphene/conducting polymer nano-composite loaded screen-printed carbon sensor for simultaneous determination of dopamine and 5-hydroxytryptamine”, Sensors and Actuators B, Elsevier, 239 (2017), 993-1002, DOI: 10.1016/j.snb.2016.08.083.
  11.  Mamta Raj, Pankaj Gupta, Neeta Thapliyal, Rajendra N. Goyal, “A novel hybrid nano-composite grafted electrochemically reduced graphene oxide based sensor for sensitive determination of efavirenz”, Electroanalysis, Wiley, 29, 2, (2017), 456-465, DOI: 10.1002/elan.201600397.
  12.  Pankaj Gupta, Rajendra N Goyal, “Amino functionalized graphene oxide and polymer nanocomposite based electrochemical platform for sensitive assay of anti-doping drug atenolol in biological fluids”, Journal of the Electrochemical Society, ECS, 163, 13, (2016), B601-B608, DOI: 10.1149/2.0281613jes.
  13.  Pankaj Gupta, Munetaka Oyama, Rajendra N. Goyal, “Electrochemical investigations of 8-hydroxydeoxyguanosine and its determination at an edge plane pyrolytic graphite electrode”, RSC Advances, RSC, 6 (2016), 1722-1728, DOI:10.1039/C5RA22682A.
  14.  Rosy, Pankaj Gupta, Rajendra N. Goyal, “High energy carbon ion beam irradiated sensor for the voltammetric sensing of purine nucleosides of DNA”, Sensors and Actuators B, Elsevier, 223 (2016), 884-892, DOI: 10.1016/j.snb.2015.10.006.
  15.  Mamta Raj, Pankaj Gupta, Rajendra N. Goyal, “Poly-Melamine film modified sensor for the sensitive and selective determination of propranolol, a β-blocker in biological fluids”, Journal of the Electrochemical Society, ECS, 163, 6, (2016), H388-H394, DOI: 10.1149/2.0411606jes.
  16.  Meruva Purushotham, Pankaj Gupta, Rajendra N. Goyal, “Graphene modified glassy carbon sensor for the determination of aspirin metabolites in human biological samples”, Talanta, Elsevier, 143 (2015), 328-334, DOI: 10.1016/j.talanta.2015.04.082.
  17.  Pankaj Gupta, Rajendra N. Goyal, “Sensitive determination of domperidone in biological fluids using a conductive polymer modified glassy carbon electrode”, Electrochimica Acta, Elsevier, 151 (2015), 1-7, DOI: 10.1016/j.electacta.2014.11.005.
  18.  Pankaj Gupta, Saurabh K. Yadav, Rajendra N. Goyal, “A Sensitive Polymelamine Modified Sensor for the Determination of Lomefloxacin in Biological Fluids”, Journal of the Electrochemical Society, ECS, 162, 1, (2015), H86-H92, DOI: 10.1149/2.0101503jes.
  19.  Pankaj Gupta, Rajendra N. Goyal, Yoon-Bo Shim, “Simultaneous analysis of dopamine and 5-hydroxyindoleacetic acid at nanogold modified screen printed carbon electrodes”, Sensors and Actuators B, Elsevier, 213 (2015), 72-81, DOI: 10.1016/j.snb.2015.02.066.
  20.  Pankaj Gupta, Rajendra N. Goyal, “Graphene and Co-polymer Composite Based Molecularly Imprinted Sensor for Ultratrace Determination of Melatonin in Human Biological Fluids”, RSC Advances, RSC, 5 (2015), 40444–40454, DOI:10.1039/C5RA04942C.
  21.  Pankaj Gupta, Rosy, Rajendra N. Goyal, “A carbon ion beam irradiated MWCNT/AuNPs composite sensor for a sensitive assay of purine- nucleosides of DNA”, RSC Advances, RSC, 5 (2015), 102300-102310, DOI:10.1039/c5ra18970e.
  22.  Pankaj Gupta, Saurabh K. Yadav, Bharati Agrawal, Rajendra N. Goyal, “A novel graphene and conductive polymer modified pyrolytic graphite sensor for determination of propranolol in biological fluids”, Sensors and Actuators B, Elsevier, 204 (2014), 791-798, DOI:10.1016/j.snb.2014.08.040.
  23.  Pankaj Gupta, Rajendra N. Goyal, “Poly melamine modified edge plane pyrolytic graphite sensor for the electrochemical assay of serotonin”, Talanta, Elsevier, 120 (2014), 17-22, DOI: 10.1016/j.talanta.2013.11.075.
  24.  Pankaj Gupta, Rajendra N Goyal, “A sensitive pyrolytic graphite sensor for determination of omeprazole in human blood plasma and pharmaceuticals”, Journal of the Electrochemical Society, ECS, 161, 1, (2014), H255-H259, DOI: 10.1149/2.093404jes.

1. Towards on-site detection of heavy metal ions in drinking water, "DST INSPIRE Fellowship" 

2. Fabrication of Electrochemical Biosensors for Therapeutically Important Biomolecules, "Industrial Project" 

Attended

Poster presentation and participation:

  • Participated in “Symposium on modern trends in inorganic chemistry-XV (MTIC-XV)”, December 13-16, 2013, Department of Chemistry, Indian Institute of Technology Roorkee.
  • P. Gupta and R.N. Goyal, Poly-melamine modified edge plane pyrolytic graphite sensor for the electrochemical assay of serotonin, 11th ISEAC International Discussion Meet on Electrochemistry and its Applications, Indian Society of Electroanalytical Chemical (ISEAC), February 20-25, 2014, Amritsar, Punjab.
  • P. Gupta and R.N. Goyal, Electrochemical investigations of omeprazole in human blood plasma and pharmaceuticals, International conference on Recent Advances in Analytical Science (RAAS-2014), March 27-29, 2014, IIT (BHU) Varanasi.
  • Participation in “Royal Society of Chemistry Roadshow and Analytical Symposium Series” organized by Royal society of chemistry, November 4, 2014, IIT Delhi.
  • P. Gupta and R.N. Goyal, Simultaneous analysis of dopamine and 5-hydroxyindoleacetic acid at size-controlled gold nanoparticles modified screen printed carbon electrodes, International conference on Recent Advances in Analytical Science (RAAS-2016), April 7-9, 2016, IIT (BHU) Varanasi.
  • P. Gupta and N.T Alvarez et. al., Electrochemistry of carbon nanotube fiber at cross-section and sidewall, Oesper Symposium, November 13, 2019, University of Cincinnati, USA.
  • G. Dangel, P. Gupta and N.T Alvarez, Development of carbon nanotube based nano channel, Oesper Symposium, November 13, 2019, University of Cincinnati, USA.
  • P. Gupta and A.S. Cans, Heat etching creates nanostructure surface roughness at carbon fiber nanotip electrodes that greatly enhances electrochemical sensitivity, Excellent Initiative Nano Community Building Activity, August 22-24, 2022, Varbergs Kusthotell, Sweden.
  • P. Gupta and Noe T. Alvarez, Electrochemistry at carbon nanotube fibers microelectrode set for the detection of biomolecules and heavy metals, International Conference on Molecular Matter- Emerging Directions for Sustainability, December 16-18, 2023, IIT Madras.

Oral presentation:

  • P. Gupta and R.N. Goyal, Determination of Melatonin Using a Sensitive Graphene and Co- polymer Composite Based Molecularly Imprinted Sensor, International Conference on Nanostructured Polymeric Materials and Polymer Nanocomposites (ICNPM 2015), November 13-15, 2015. Mahatma Gandhi University, Kerala.
  • SPEAKER at the 3rd seminar series “TERCER CICLO DE CONFERENCIAS INTERNACIONALES SOBRE NANOTECNOLOGÍA Y CIENCIA DE MATERIALES”, organized by the University of Cincinnati for Latin American undergraduate students from Universities in Mexico, Peru and Bolivia from March 22nd to May 3rd of 2023.

Workshop:

  • Attended workshop on “Nano Drug Delivery System (Industry-Academia Interaction)” organized by Centre of Excellence: Nanotechnology, IIT Roorkee, January 2015.
  • Attended workshop on “Checking of Plagiarism in scientific writing using Turnitin Software” organized by Mahatma Gandhi Central Library, IIT Roorkee, April 2015.
  • Attended workshop on “Using Web of Science for Research”, organized by Mahatma Gandhi Central Library, IIT Roorkee, Feb. 2015.
  • Attended workshop on “2D Materials, Electrical: Contacts, Process and Device Applications” at MC2 organized by Chalmers university of technology, Sweden, November 2022.
  • Attended “Community Building Day in Health Engineering” organized by Health Engineering Area of Advance, Chalmers University of technology, Sweden, May 2023.
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