Personal Information

Dr. Shailendra Pratap Singh

Assistant Professor

Ph.D. Biotechnology, CSIR-Indian Institute of Chemical Technology, Hyderabad. CSIR-NET LS, ICMR-SRF Post-Doc.- Kansas University Medical Center, USA; Post-Doc., Research Scientist- NYMC, New York, USA (2013-2020); Visiting Faculty- NYMC, New York, USA,

spsingh@curaj.ac.in

8287230934

Sudden Cardiac Arrest; Metabolic Syndrome: High Blood Pressure and abnormal Cholesterol levels; Diabetes & Insulin Resistance; Cardiovascular Diseases; Kidney damage and Fibrosis;

Our study aims to find a new target and the molecular processes that govern changes in metabolism, sudden cardiac arrest, metabolic rate, oxygen use, and insulin sensitivity in skeletal muscle, cardiac muscle, adipose tissue, and during normal activity as well as sports and exercise. PGC-1a is connected to turning on genes that help with fatty acid oxidation and mitochondrial biogenesis. It also raises the expression of GLUT4 in muscle cells. The mitochondrial respiratory chain is the means by which ATP is generated within mitochondria, the cellular powerhouses

 

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Education

  • Ph.D. Biotechnology, CSIR-Indian Institute of Chemical Technology, Hyderabad. 
  • Post-Doc., Kansas University Medical Center, Kansas, USA
  • Post-Doc., New York Medical College, New York, USA.
  • Research Scientist- New York University, New York, USA

Visiting Professor 

  • Visiting Faculty: New York Medical College, New York, USA
  • Visiting professor at the Center for Higher Studies in Human and Health Sciences at the Inter-American Open University in Buenos Aires, Argentina
  • Visiting professor at the Petrovsky National Research Center of Surgery, Russia, Moscow

Fellowship/ Awards

  • CSIR-UGC-National EligibilityT est (National Aptitude Screening Test conducted by CSIR-UGC), GOI, New Delhi, 2007.
  • Junior Research Fellow-Project, IICT Hyderabad (Department of Biotechnology, New Delhi), 2008
  • Senior Research Fellow-Project (Indian Council of Medical Research, New Delhi), 2011
  • 2018 Cell Signaling Technology, USA, Grant Program Grand Prize Winner of USD 5000
  • The most innovative faculty of the year 2020 was given by the DHS Foundation, New Delhi, in collaboration with Campbell University, North Carolina, USA.
  • Research Excellence Award 2020 by Institute of Scholars (InSc)
  • Awarded UGC-Funded-DSKothari Postdoctoral fellowship 2020
  • I was selected for the Scientist II position in the Department of Anatomy at the All India Institute of Medical Sciences in New Delhi, India but Prefer to join CURAJ
  • Awarded with Best Paper Presenter in the International Conference on Emerging Need to Strengthen Global Public Health Policy and Sports Sciences 2023, organized by SMIT, India, held on February 25–27.
  • Co-Chairman of the 3rd Technical Session at the 7TH NATIONAL CONFERENCE OF SPORTS SCIENCES PEFI, held in New Delhi.

WORK EXPERIENCE

  • January 2020 – May 2022 with the Central University of Rajasthan as an Assistant Professor in the Department of Biomedical Engineering
  • Awarded National Institutes of Health (NIH), USA Sponsored Research Scientist Position 2018 - 2020 with New York Medical College, New York, USA, Department of Pharmacology 
  • Awarded National Institutes of Health (NIH), USA Sponsored Postdoctoral Research Position 2015 - 2018 with New York Medical College, New York, the USA
  • Awarded National Institutes of Health (NIH), USA Sponsored Postdoctoral Research Position  2013 - 2015 with The Kidney Institute, Kansas University Medical Center, the USA

 

 

 

 

 

 

 

 

 

My lab is working on 

  • Sports Biochemistry
  • Sports Nutrition
  • Sports Physiology

Finding new targets for metabolic syndrome (MetS) includes obesity, high cholesterol, insulin resistance, and high blood pressure. Coronary heart disease and heart attacks are more likely in metabolic syndrome. In metabolic cardiomyopathy, there are structural and functional abnormalities, interstitial fibrosis, and no coronary artery disease or hypertension symptoms. Muscle has endocrine and paracrine activities. Myokines are muscle proteins that allow communication with the liver, adipose tissue, pancreas, bone, and cardiovascular system. Reduced physical activity and sarcopenia (muscle mass and strength loss) contribute to senior frailty and impairment. Coronary heart disease and heart attack are more common in metabolic syndrome. In metabolic cardiomyopathy, structural and functional alterations and interstitial fibrosis occur without coronary artery disease or excessive blood pressure. The muscle is an endocrine and paracrine organ. Skeletal muscle mass, the pancreas, bone, liver, adipose tissue, and cardiovascular system interact with myokine-derived secretory proteins. Scapopenia (loss of lean muscle mass and strength) and declining physical activity are associated with frailty and impairment in the elderly.

 

Editor of International Journals: 

  • Frontier in Pharmacology
  • Biomedicines
  • International Journal of Molecular Sciences
  • Journal of Obesity 
  • Biomedical Research and Practice
  • Journal of Cell Biology 
  • Journal of Cardiology
  • Reviewer of International Journals:
  • Frontier in Pharmacology
  • Biomedicines
  • International Journal of Molecular Sciences
  • Journal of Obesity 
  • Biomedical Research and Practice
  • Journal of Cell Biology 
  • Journal of Cardiology
  • PLOM
  • Cells
  • International Journal of Obesity
  • Cardiovascular diseases

 

 

 

 

 

 

 

 

 

S. No. Authors Title of Article Journal/Conference Details Journal/Conference Publication Year
1 1
  • PI-Received Rs.10,00000/- INR of Seed Grant 2022 by CuRaj.
  • PI-Project titled "The impact of various factors on the permeability of the endothelial barrier in the pathogenesis of cardiovascular diseases; the development of corrective therapies.". By DST-SERB for Rs. 31,50000/- INR 2023
  • Co-PI-Titled “Establishment of inclusive TBI at Central University of Rajasthan” submitted for setting up Inclusive Technology Business Incubator (i-TBI). By DST for Rs. 5,29,09000/-INR

PATENT: Details of Patent “Edible Oil Quality Monitoring Device” (The patent office journal No.52/2022 dated 30/12/2022; P.81600) date of publication 30-12-2022

Sr No.

CUPB/
CUHP/ EXTERNAL

Title

Inventor

Filing Date

Application No

Publication date

Journal No.

 

713

PB

EDIBLE OIL QUALITY MONITORING SYSTEM

PRATEEK SRIVASTAVA, JASMINDER K SANDHU, DEEPAM GOYAL, S K MITTAL, SHAILENDRA PARTAP SINGH, ASHIWANI KUMAR

02-12-2022

202211069733

30-12-2022

52/2022

The Patent Office Journal No. 52/2022 Dated 30/12/2022 P. 81600

 

 

 

 

 

 

 

 

Attended

MEMBERSHIPS

  • American Society for Pharmacology and Experimental Therapeutics
  • American Association for the Advancement of Science (AAAS- 60044979)
  • The New York Academy of Sciences (NYAS)

CONFERENCE/MEETINGS:

  • American society of nephrology meeting, San Diego (USA), 2015
  • American Heart Association meeting, Orlando Florida (USA) 2016
  • 17th International Winter Eicosanoid Conference, Baltimore, MD (USA) 2018  
  • American Diabetes Association (ADA -548271899
  • The Purina institute microbiome forum virtual events 2021, October 20-21 2021. Putting microbiome science in to clinical Practice. St Louis Missouri, USA.

  • National Bioengineering conference 2022, 6-7th Jan 2022, NIT Rourkela, India

  • Awarded with Best paper presenter in the International Conference on Emerging Need to Strengthen Global Public Health Policy and Sports Sciences -2023 organized SMIT, India, held on 25-27th February.
  • Co-Chairman at 3rd Technical session at 7TH NATIONAL CONFERENCE OF SPORTS SCIENCES PEFI, New Delhi

BEYOND WORK: - EDITORIALS & PANEL JUDGING: NOTABLE ACCOMPLISHMENTS ACROSS THE CAREER

  • Academic editor in different Journals (A) A) Frontiers in Pharmacology, section Experimental Pharmacology and Drug Discovery; (B) Biomedicines (C) Vaccines (D) Vaccines(https://www.mdpi.com/journal/vaccines).
  • Served as a Poster Judge many times at the Summer Training in Academic Research (STAR) research forum, GSRF- Graduate senior research forum at New York Medical College, New York, USA. Invited to Judge a poster session at Westchester Science and Engineering Fair -An INTEL-ISEF affiliated fair AT Sleepy Hollow High School 210 North Broadway, Sleepy Hollow, and NY 10591 ON Saturday, March 17, 2018
  • Serving as a reviewer for more than 20 research Journals with high impact factors and reviewed more than 100 research articles from very high impact factor journals i.e. International Journal of nanomedicine,  Clinical Interventions in Aging, Journal of Experimental Pharmacology, Diabetes, Metabolic Syndrome, and Obesity: Targets and Therapy, Frontier in pharmacology, Stem cell international, Cellular physiology and biochemistry, Cardiovascular Therapeutics, Canadian Journal of Physiology and Pharmacology, Colloids and Surfaces B and PLOS ONE
  • Analytical biochemistry paper was highlighted by nature India News 2012  which comprised of Technique to screen anti-diabetic drugs. Indian Institute of Chemical Technology, Hyderabad: Development of a cell-based nonradioactive glucose uptake assay system for SGLT1 and SGLT2
  • The research was used as a reference for a method by Detroit R&D, MI, USA to measure Mito copy no (Mitochondrial Copy Number PCR-Based Kits Real-Time PCR DNA Mitochondrial Quantification for Human, Mouse, and Rat).

FDPs/Orientations/Refresher course

  • Attended 21 days of FDP/Orientation/TLC course in January 2021
  • Attended 15 days Refresher course in research methodology from Jan. 23, 2023 - Feb. 6, 2023
  • Attended 7days FDP course on National Education Policy-2020 from 20-26 March, 2023

Invited Talk

  • Invited talk given at MDS University, Ajmer on "Metabolic syndrome with special reference to diabetes and Cardiovascular diseases," December 23, 2022.
  • Awarded with Best paper presenter in the International Conference on Emerging Need to Strengthen Global Public Health Policy and Sports Sciences -2023 organized SMIT, India, held on 25-27th February.

 

Organized